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Within the field of developmental biology, one goal is to understand how a particular cell develops into a final cell type, known as fate determination.Within an embryo, several processes play out at the cellular and tissue level to create an organism.
In 2020, it was announced that Google's AlphaFold, a neural network based on DeepMind artificial intelligence, is capable of predicting a protein's final shape based solely on its amino-acid chain with an accuracy of around 90% on a test sample of proteins used by the team.
Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. [1] The use of the word cloning refers to the fact that the method involves the replication of one molecule to produce a population of cells with identical DNA molecules.
These "rate-distortion" models [107] suggest that the genetic code originated as a result of the interplay of the three conflicting evolutionary forces: the needs for diverse amino acids, [108] for error-tolerance [103] and for minimal resource cost. The code emerges at a transition when the mapping of codons to amino acids becomes nonrandom.
[5] There are 64 different codons in the genetic code and the below tables; most specify an amino acid. [6] Three sequences, UAG, UGA, and UAA, known as stop codons, [note 1] do not code for an amino acid but instead signal the release of the nascent polypeptide from the ribosome. [7]
The presence of an active β-galactosidase can be detected by X-gal, a colourless analog of lactose that may be cleaved by β-galactosidase to form 5-bromo-4-chloro-indoxyl, which then spontaneously dimerizes and oxidizes to form a bright blue insoluble pigment 5,5'-dibromo-4,4'-dichloro-indigo. This results in a characteristic blue colour in ...
Computational genomics refers to the use of computational and statistical analysis to decipher biology from genome sequences and related data, [1] including both DNA and RNA sequence as well as other "post-genomic" data (i.e., experimental data obtained with technologies that require the genome sequence, such as genomic DNA microarrays).
The genotype of an organism is its complete set of genetic material. [1] Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. [2]