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  2. Upstream and downstream (transduction) - Wikipedia

    en.wikipedia.org/wiki/Upstream_and_downstream...

    The first group of type I receptors (Alk1/2/3/6) bind and activate the R-Smads, Smad1/5/8. The second group of type I reactors (Alk4/5/7) act on the R-Smads, Smad2/3. The phosphorylated R-Smads then form complexes and the signals are funneled through two regulatory Smad (R-Smad) channels (Smad1/5/8 or Smad2/3).

  3. Upstream and downstream (DNA) - Wikipedia

    en.wikipedia.org/wiki/Upstream_and_downstream_(DNA)

    This means the upstream and downstream areas of the molecule may change depending on which gene is used as the reference. The terms upstream and downstream are sometimes also applied to a polypeptide sequence, where upstream refers to a region N-terminal and downstream to residues C-terminal of a reference point.

  4. Upstream and downstream - Wikipedia

    en.wikipedia.org/wiki/Upstream_and_downstream

    Upstream and Downstream, the notional directions which lie "towards" and "away from" the author of a piece of software, relative to the speaker See also [ edit ]

  5. Downstream - Wikipedia

    en.wikipedia.org/wiki/Downstream

    Downstream may refer to: Downstream (hydrology) , the direction towards the mouth of a stream, i.e. the direction the current flows Downstream (bioprocess) , when a cell mass from an upstream process (isolated, grown and harvested) is further processed to meet purity and quality requirements

  6. Bioprocess - Wikipedia

    en.wikipedia.org/wiki/Bioprocess

    Therapeutic cell manufacturing processes can be separated into upstream processes and downstream processes. The upstream process is defined as the entire process from early cell isolation and cultivation, to cell banking and culture expansion of the cells until final harvest (termination of the culture and collection of the live cell batch).

  7. Phylogenetic tree - Wikipedia

    en.wikipedia.org/wiki/Phylogenetic_tree

    A phylogenetic tree, phylogeny or evolutionary tree is a graphical representation which shows the evolutionary history between a set of species or taxa during a specific time. [ 1 ] [ 2 ] In other words, it is a branching diagram or a tree showing the evolutionary relationships among various biological species or other entities based upon ...

  8. Biological organisation - Wikipedia

    en.wikipedia.org/wiki/Biological_organisation

    A population of bees shimmers in response to a predator. Biological organisation is the organisation of complex biological structures and systems that define life using a reductionistic approach. [1]

  9. Downstream promoter element - Wikipedia

    en.wikipedia.org/wiki/Downstream_promoter_element

    In molecular biology, a downstream promoter element (DPE) is a core promoter element. Like all core promoters, the DPE plays an important role in the initiation of gene transcription by RNA polymerase II. The DPE was first described by T. W. Burke and James T. Kadonaga in Drosophila melanogaster at the University of California, San Diego in ...