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Sarcopenia (ICD-10-CM code M62.84 [1]) is a type of muscle loss that occurs with aging and/or immobility. It is characterized by the degenerative loss of skeletal muscle mass, quality, and strength. The rate of muscle loss is dependent on exercise level, co-morbidities, nutrition and other factors.
Compared to other tissues in the body, the brain is deemed unusually sensitive to oxidative damage. [24] Increased oxidative damage has been associated with neurodegenerative diseases, mild cognitive impairment and individual differences in cognition in healthy elderly people. In 'normal aging', the brain is undergoing oxidative stress in a ...
In the elderly, this often leads to decreased biological reserve and increased vulnerability to stressors known as the "frailty syndrome." [3] Loss of lean body mass is also associated with increased risk of infection, decreased immunity, and poor wound healing. The weakness that accompanies muscle atrophy leads to higher risk of falls ...
Osteoporosis can affect nearly 1 in 3 women and the bone loss is the most rapid within the first 2–3 years after menopause. This can be prevented by menopause hormone therapy or MHT, which is meant to prevent bone loss and the degradation of the bone microarchitecture and is noted to reduce the risk of fractures in bones by 20-30%.
Many elderly people gradually lose functioning ability and require either additional assistance in the home or a move to an eldercare facility. [37] Their adult children often find it challenging to help their elderly parents make the right choices. [38] Assisted living is one option for the elderly who need assistance with everyday tasks.
The primary sites of end-target organ damage following an increase in arterial stiffness are the heart, the brain (stroke, white matter hyperintensities (WMHs)), the placenta, and the kidneys (age-related loss of kidney function). [21] Firstly, stiffened arteries compromise the Windkessel effect of the arteries. [22]
This tissue is thus the initial site where pathogenic agents, such as bacteria that have breached an epithelial surface, are challenged and destroyed by cells of the immune system. [1] In the past, the designations areolar tissue, adipose tissue, and reticular tissue have been listed as subsets of loose connective tissue. However, they are no ...
Scar tissue is composed of the same protein as the tissue that it replaces, but the fiber composition of the protein is different; instead of a random basketweave formation of the collagen fibers found in normal tissue, in fibrosis the collagen cross-links and forms a pronounced alignment in a single direction. [1]