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  2. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...

  3. Allopurinol hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Allopurinol...

    Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...

  4. Febuxostat - Wikipedia

    en.wikipedia.org/wiki/Febuxostat

    Febuxostat is used to treat chronic gout and hyperuricemia. [12] Febuxostat is typically recommended only for people who cannot tolerate allopurinol. [13] National Institute for Health and Clinical Excellence concluded that febuxostat is more effective than standard doses of allopurinol, but not more effective than higher doses of allopurinol.

  5. Uricosuric - Wikipedia

    en.wikipedia.org/wiki/Uricosuric

    Drugs with other primary uses, that have known uricosuric properties, include losartan, [1] atorvastatin, and fenofibrate.Although these drugs may have significant uricosuric action, their other significant pharmacological actions in off-label use as a uricosuric requires careful assessment of the patient to achieve the most benefit and least risk.

  6. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Probenecid can be used in a combined therapy with allopurinol is more effective than allopurinol monotherapy. [76] [77] [78] Pegloticase is an option for the 3% of people who are intolerant to other medications. [79] It is a third line agent. [64] Pegloticase is given as an intravenous infusion every two weeks, [79] and reduces uric acid levels ...

  7. 3 Key Signs You Might Not Qualify for the Social Security ...

    www.aol.com/3-key-signs-might-not-120029623.html

    Social Security serves as a lifeline for tens of millions of seniors. Today, that number is growing. As of December 2024, the Social Security Administration (SSA) reported that about 65.5 million...

  8. 20 Turmeric Recipes for an Anti-Inflammatory Boost - AOL

    www.aol.com/20-turmeric-recipes-anti...

    This laksa ayam is a delightful twist on traditional Southeast Asian laksa, offering a lower-carb but still deeply satisfying meal. The homemade spice paste is the heart of the dish, infusing the ...

  9. Neuromuscular-blocking drug - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular-blocking_drug

    Although having many unwanted side-effects, a slow onset of action and recovery rate it was a big success and at the time the most potent neuromuscular drug available. Pancuronium and some other neuromuscular blocking agents block M2-receptors and therefore affect the vagus nerve , leading to hypotension and tachycardia .