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  2. US FDA approves Novo Nordisk's Ozempic to cut risk of ... - AOL

    www.aol.com/news/us-fda-approves-novo-nordisks...

    The approval was based on data from a late-stage study, which showed that Ozempic helped cut the risk of death from chronic kidney disease and major cardiac events by 24%, the company said.

  3. Semaglutide - Wikipedia

    en.wikipedia.org/wiki/Semaglutide

    In December 2016, a New Drug Application was filed with the US Food and Drug Administration (FDA), and in October 2017, a FDA advisory committee approved it unanimously. [65] In December 2017, the injectable version with the brand name Ozempic was approved for use by people with diabetes in the United States, [30] [66] and, in January 2018, in ...

  4. FDA approves Ozempic to reduce risks from chronic kidney ...

    www.aol.com/news/fda-approves-ozempic-reduce...

    Ozempic, the blockbuster GLP-1 drug that was originally approved to treat type 2 diabetes, has now also been approved by the US Food and Drug Administration to reduce certain risks associated with ...

  5. How Long Have Semaglutide Drugs Like Ozempic and Wegovy ... - AOL

    www.aol.com/long-semaglutide-drugs-ozempic...

    Ozempic. Ozempic was FDA-approved in December 2017 as a diabetes drug. It’s prescribed off-label for weight loss. ... (Byetta) and liraglutide (Victoza and Saxenda) were developed. Byetta was ...

  6. Encorafenib - Wikipedia

    en.wikipedia.org/wiki/Encorafenib

    Encorafenib is indicated in combination with binimetinib, for the treatment of people with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test; [2] in combination with cetuximab, for the treatment of adults with metastatic colorectal cancer with a BRAF V600E mutation, as detected by an FDA-approved test, after prior therapy; [2] in ...

  7. MEK inhibitor - Wikipedia

    en.wikipedia.org/wiki/MEK_inhibitor

    Cobimetinib or XL518, approved by US FDA in Nov 2015 for use in combination with vemurafenib (Zelboraf(R)), for treatment of advanced melanoma with a BRAF V600E or V600K mutation. Selumetinib , had a phase 2 clinical trial for non-small cell lung cancer (NSCLC) which demonstrated an improvement in PFS, [ 5 ] and is now in phase III development ...

  8. BRAF (gene) - Wikipedia

    en.wikipedia.org/wiki/BRAF_(gene)

    Certain other inherited BRAF mutations cause birth defects. Drugs that treat cancers driven by BRAF mutations have been developed. Two of these drugs, vemurafenib [8] and dabrafenib, are approved by FDA for treatment of late-stage melanoma. Vemurafenib was the first approved drug to come out of fragment-based drug discovery. [9]

  9. Denmark also uses Ozempic’s sister drug approved for weight loss, Wegovy, and has similarly grappled with the cost, questioning whether its benefits justify them.

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