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MLA Handbook grew out of the initial MLA Style Sheet of 1951 [5] (revised in 1970 [6] [7]), a 28-page "more or less official" standard. [8] The first five editions, published between 1977 and 1999 were titled MLA Handbook for Writers of Research Papers, Theses, and Dissertations.
A type of research study that tests how well new medical approaches work in people. These studies test new methods of screening, prevention, diagnosis, or treatment of a disease. Also called a clinical trial. (NCI) A clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known ...
A clinical control group can be a placebo arm or it can involve an old method used to address a clinical outcome when testing a new idea. For example in a study released by the British Medical Journal, in 1995 studying the effects of strict blood pressure control versus more relaxed blood pressure control in diabetic patients, the clinical control group was the diabetic patients that did not ...
A quasi-experiment is an empirical study used to estimate the causal impact of an intervention. Quasi-experiments shares similarities with experiments or randomized controlled trials, but specifically lack random assignment to treatment or control. Instead, quasi-experimental designs typically allow assignment to treatment condition to proceed ...
ITT analysis is intended to avoid various misleading artifacts that can arise in intervention research such as non-random attrition of participants from the study or crossover. ITT is also simpler than other forms of study design and analysis, because it does not require observation of compliance status for units assigned to different ...
Comparative effectiveness research (CER) is the direct comparison of existing health care interventions to determine which work best for which patients and which pose the greatest benefits and harms. The core question of comparative effectiveness research is which treatment works best, for whom, and under what circumstances. [ 1 ]
In social studies and social policy, intervention theory is the analysis of the decision making problems of intervening effectively in a situation in order to secure desired outcomes. Intervention theory addresses the question of when it is desirable not to intervene and when it is appropriate to do so.
One significant issue with parallel studies, though, is the concept of intra subject variability, which is defined as variability in response occurring within the same patient. [1] The two treatment groups in a parallel study can either consist of two completely separate treatments (i.e. different drugs), or simply different doses of a common drug.