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18101 Prince Philip Drive, Olney, Maryland, United States Coordinates 39°9′14.1″N 77°3′16.9″W / 39.153917°N 77.054694°W / 39.153917; -77.
Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor.
John Olney (1932 – April 14, 2015) was a medical doctor and a professor of psychiatry, pathology, and immunology at the Washington University School of Medicine. He is known for his work on brain damage. He coined the term excitotoxicity [1] in his 1969 paper published in Science. [2] Olney's lesions are named after him.
The main subtypes of frontotemporal dementia are behavioral variant FTD (bvFTD), two variants of primary progressive aphasia – semantic dementia (svPPA) and progressive nonfluent aphasia (nfvPPA) [4] [18] – as well as FTD associated with amyotrophic lateral sclerosis (FTD–ALS or FTD-MND). [15]
Richard Koch Olney (December 15, 1947 – January 27, 2012) was an American physician who was a pioneer in clinical research on amyotrophic lateral sclerosis (ALS). He was born in Munich, Germany. He was the founder and director of the ALS Treatment and Research Center at the University of California, San Francisco. In 2004 he was forced to ...
Paul B. Baltes (18 June 1939 – 7 November 2006) was a German psychologist whose broad scientific agenda was devoted to establishing and promoting the life-span orientation of human development. He was also a theorist in the field of the psychology of aging.
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