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The use of chan'su and love stone (a related toad skin preparation used as an aphrodisiac in the West Indies) has resulted in several cases of poisoning and at least one death. [24] [28] The practice of orally ingesting toad poison has been referred to in popular culture and in the scientific literature as toad licking and has drawn media ...
While most common psychedelics are believed to primarily elicit psychological effects through agonism of serotonin 5-HT 2A receptors, 5-MeO-DMT shows 1,000-fold greater affinity for 5-HT 1A over 5-HT 2A; [26] In line with its affinity for 5-HT 1A receptors, 5-MeO-DMT is extremely potent at suppressing the firing of dorsal raphe 5-HT neurons. [27]
They occur in the parotoid glands, skin, and poison of many toads (Bufonidae family) and other amphibians, and in some plants and mushrooms. [ 1 ] [ 2 ] [ 3 ] The exact composition varies greatly with the specific source of the toxin.
The parotoid gland (alternatively, paratoid gland) is an external skin gland on the back, neck, and shoulder of some frogs (especially toads), and salamanders. It can secrete a number of milky alkaloid substances (depending on the species) known collectively as bufotoxins , which act as neurotoxins to deter predation .
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Weight loss, a possible treatment for opioid use disorder, and reduced risks for heart disease, stroke, and a slew of other diseases—those are just some of the benefits of Ozempic, the type 2 ...
Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3]