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Whipple's triad is a collection of three signs (called Whipple's criteria) that suggests that a patient's symptoms result from hypoglycaemia that may indicate insulinoma.The essential conditions are symptoms of hypoglycaemia, low blood plasma glucose concentration, and relief of symptoms when plasma glucose concentration is increased.
Most neurons have the ability to use other fuels besides glucose (e.g. lactic acid, ketones).Knowledge of the "switchover" process is incomplete. [further explanation needed] The most severe neuroglycopenic symptoms occur with hypoglycemia caused by excess insulin because insulin reduces the availability of other fuels by suppressing ketogenesis and gluconeogenesis.
This is an accepted version of this page This is the latest accepted revision, reviewed on 4 February 2025. Group of endocrine diseases characterized by high blood sugar levels This article is about the common insulin disorder. For the urine hyper-production disorder, see Diabetes insipidus. For other uses, see Diabetes (disambiguation). Medical condition Diabetes Universal blue circle symbol ...
[1] [3] [9] The treatment of hypoglycemia unrelated to diabetes includes treating the underlying problem. [3] [2] Among people with diabetes, prevention starts with learning the signs and symptoms of hypoglycemia. [3] [2] Diabetes medications, like insulin, sulfonylureas, and biguanides can also be adjusted or stopped to prevent hypoglycemia.
A medical sign is an objective observable indication of a disease, injury, or medical condition that may be detected during a physical examination. [7] These signs may be visible, such as a rash or bruise, or otherwise detectable such as by using a stethoscope or taking blood pressure.
Hyperosmolar hyperglycemic state (HHS), also known as hyperosmolar non-ketotic state (HONK), is a complication of diabetes mellitus in which high blood sugar results in high osmolarity without significant ketoacidosis. [4] [5] Symptoms include signs of dehydration, weakness, leg cramps, vision problems, and an altered level of consciousness. [2]
Pathognomonic (synonym pathognomic [1]) is a term, often used in medicine, that means "characteristic for a particular disease".A pathognomonic sign is a particular sign whose presence means that a particular disease is present beyond any doubt.
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. [6] Common symptoms include increased thirst , frequent urination , fatigue and unexplained weight loss . [ 3 ]