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Belimumab, sold under the brand name Benlysta, is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), [6] also known as B-lymphocyte stimulator (BLyS). [7] It is approved in the United States [ 8 ] and Canada, [ 9 ] and the European Union [ 5 ] to treat systemic lupus erythematosus and lupus nephritis.
The US Food and Drug Administration (FDA) granted the application for belantamab mafodotin priority review, orphan drug, and breakthrough therapy designations. [ 5 ] In 2023, the confirmatory phase III DREAMM-3 trial aimed to compare belantamab mafodotin versus pomalidomide plus low-dose dexamethasone in participants with relapsed or refractory ...
Tooth pathology is any condition of the teeth that can be congenital or acquired. Sometimes a congenital tooth disease is called a tooth abnormality.These are among the most common diseases in humans [1] The prevention, diagnosis, treatment and rehabilitation of these diseases are the base to the dentistry profession, in which are dentists and dental hygienists, and its sub-specialties, such ...
From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) the international nonproprietary name (INN).
The contact can affect cuspal, incisal and proximal surface areas. [2] Indications of attrition can include: [3] Loss of tooth anatomy: This results in loss of tooth characteristics including rounding or sharpening of incisal edges, loss of cusps and fracturing of teeth. Enamel of molar teeth may appear thin and flat.
Double teeth are more common in primary teeth with a prevalence of 0.5 - 0.7%, but can occur in permanent teeth. [1] Unlike tooth fusion, tooth gemination is more common in the maxillary incisors and canines. [3] [4] [5] Like tooth gemination, tooth fusion is more common in the anterior teeth (incisors and canines). Double teeth affect both ...
Additionally, there have been instances of fake reviews and defamation on the site, leading to questions about the reliability of the information available. RateMDs.com has also faced criticism for its earlier practice of allowing healthcare providers to pay to suppress negative ratings through the Rating Manager feature.
Currently, the anti-caries effect fluoride varnishes are backed up by Cochrane systematic reviews, 2002 which was updated in 2013 included 22 trials with 12,455 children aged 1–15 years old. The conclusion made is similar to its previous review, a 46% reduction in D(M)FS and 33% reduction in d (e/m)fs in permanent teeth and deciduous teeth ...