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Risk factors for kidney disease include diabetes, high blood pressure, family history, older age, ethnic group and smoking. For most patients, a GFR over 60 (mL/min)/(1.73 m 2) is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention.
Kidney stones can result from an underlying metabolic condition, such as distal renal tubular acidosis, [21] Dent's disease, [22] hyperparathyroidism, [23] primary hyperoxaluria, [24] or medullary sponge kidney. 3–20% of people who form kidney stones have medullary sponge kidney. [25] [26]
[citation needed] A large "staghorn" kidney stone may block all or part of the renal pelvis. The size of the renal pelvis plays a major role in the grading of hydronephrosis . Normally, the anteroposterior diameter of the renal pelvis is less than 4 mm in fetuses up to 32 weeks of gestational age and 7 mm afterwards. [ 2 ]
An intravenous pyelogram is used to look for problems relating to the urinary tract. [5] These may include blockages or narrowing, such as due to kidney stones, cancer (such as renal cell carcinoma or transitional cell carcinoma), enlarged prostate glands, and anatomical variations, [5] such as a medullary sponge kidney. [6]
The length of the adult kidney is normally 10–12 cm, and the right kidney is often slightly longer than the left kidney. The adult kidney size is variable due to the correlation with body height and age; however, normograms for pediatric kidney size are available. [1]
In pyeloscopy, the endoscope is designed to reach all the way to the renal pelvis (also called pyelum), thereby allowing visualisation of the entire drainage system of the kidney. [3] The endoscope can contain an instrument port which allows for introduction of laser fibres to fragment stones, and micro-baskets to retrieve stone fragments. [ 3 ]
Many stone types can be detected by ultrasound; Factors contributing to stone formation (as in #Etiology) are often tested: Laboratory testing can give levels of relevant substances in blood or urine; Some stones can be directly recovered (at surgery, or when they leave the body spontaneously) and sent to a laboratory for analysis of content
Renal biopsy (also kidney biopsy) is a medical procedure in which a small piece of kidney is removed from the body for examination, usually under a microscope. [1] Microscopic examination of the tissue can provide information needed to diagnose, monitor or treat problems of the kidney.
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