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  2. Nomenclature of monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/Nomenclature_of_monoclonal...

    The nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to monoclonal antibodies.An antibody is a protein that is produced in B cells and used by the immune system of humans and other vertebrate animals to identify a specific foreign object like a bacterium or a virus.

  3. Bispecific monoclonal antibody - Wikipedia

    en.wikipedia.org/wiki/Bispecific_monoclonal_antibody

    As an example, AFM 11 is based on the TandAbs platform and targets both CD3 and CD19 to achieve therapeutic effects. AFM 11 showed dose-dependent inhibition of Raji tumors in vivo . [ 19 ] The Bi-Nanobody platform forms multi-specific binding through the connection between the VH regions of two or more antibody molecules.

  4. Biological target - Wikipedia

    en.wikipedia.org/wiki/Biological_target

    The term "biological target" is frequently used in pharmaceutical research to describe the native protein in the body whose activity is modified by a drug resulting in a specific effect, which may be a desirable therapeutic effect or an unwanted adverse effect. In this context, the biological target is often referred to as a drug target.

  5. Simplified Molecular Input Line Entry System - Wikipedia

    en.wikipedia.org/wiki/Simplified_Molecular_Input...

    SMILES generation algorithm for ciprofloxacin: break cycles, then write as branches off a main backbone. The Simplified Molecular Input Line Entry System (SMILES) is a specification in the form of a line notation for describing the structure of chemical species using short ASCII strings.

  6. List of Target brands - Wikipedia

    en.wikipedia.org/wiki/List_of_Target_brands

    Made By Design, a homelines brand, made up of home basics such as towels, cooking utensils, glassware, plates, pots, kitchen gadgets, and more; Smartly, an essential commodity brand, including household, healthcare, beauty, and personal-care products; Gigglescape, a children's toy brand [21]

  7. Cell survival curve - Wikipedia

    en.wikipedia.org/wiki/Cell_survival_curve

    The repair model, instead of the target theory, emphasizes how a cell utilizes said cell’s repair mechanisms up to the limit of the cell’s repair machinery (the end of the shoulder). After the limit of the cell’s machinery is reached, the repair model generally notes that if any damage is left unhealed the dying process will be initiated.

  8. Sample size determination - Wikipedia

    en.wikipedia.org/wiki/Sample_size_determination

    using a target variance for an estimate to be derived from the sample eventually obtained, i.e., if a high precision is required (narrow confidence interval) this translates to a low target variance of the estimator. the use of a power target, i.e. the power of statistical test to be applied once the sample is collected.

  9. Transformation efficiency - Wikipedia

    en.wikipedia.org/wiki/Transformation_efficiency

    Here is an example of how to calculate transformation efficiency using colony forming units (CFUs): [3] Plate a known number of cells on agar plates containing the appropriate antibiotics. Incubate the plates for a period of time (usually overnight) at the appropriate temperature and conditions for the cells.