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While the FDA hasn’t approved oral minoxidil for hair loss, clinical trials have shown it’s quite effective for hair growth at various doses (0.25 to 2.5 mg daily). Spironolactone .
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Spironolactone can be used in the treatment of female-pattern hair loss (pattern scalp hair loss in women). [69] There is tentative low quality evidence supporting its use for this indication. [70] Although apparently effective, not all cases of female-pattern hair loss are dependent on androgens. [71]
Androgenetic alopecia, or male pattern baldness, is a common form of hair loss that can occur in your 20s, 30s, 40s or later in your life Over time, this hair loss may cause your frontal hairline ...
The AR antagonism of spironolactone mostly underlies its antiandrogenic activity and is the major mechanism responsible for its therapeutic benefits in the treatment of androgen-dependent conditions like acne, hirsutism, and pattern hair loss and its usefulness in hormone therapy for transgender women.
Minoxidil, applied topically, is widely used for the treatment of hair loss. It may be effective in helping promote hair growth in both men and women with androgenic alopecia. [20] [21] About 40% of men experience hair regrowth after 3–6 months. [22] It is the only topical product that is FDA approved in America for androgenic hair loss. [20]
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