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Potentiates warfarin activity, leading to excessive anticoagulation and bleeding [3] [13] Dong quai female ginseng Angelica sinensis: May induce uterine contractions; contraindicated when pregnant or nursing [14] European Mistletoe: common mistletoe Viscum album: Toxic to cardio and central nervous systems, gastrointestinal bleeding [3] Ephedra ...
Warfarin is indicated for the prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism; [9] prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation and/or cardiac valve replacement; [9] and reduction in the risk of death, recurrent myocardial infarction, and thromboembolic events such as stroke or systemic embolization after ...
It is used to treat certain bleeding disorders, [7] including warfarin overdose, vitamin K deficiency, and obstructive jaundice. [7] Use is typically recommended by mouth, intramuscular injection or injection under the skin. [7] When given by injection benefits are seen within two hours. [7]
Dysgeusia, also known as parageusia, is a distortion of the sense of taste. Dysgeusia is also often associated with ageusia, which is the complete lack of taste, and hypogeusia, which is a decrease in taste sensitivity. [1] An alteration in taste or smell may be a secondary process in various disease states, or it may be the primary symptom.
Warfarin necrosis is a rare but severe complication of treatment with warfarin or related anticoagulants. [2] The typical patient appears to be an obese, middle aged woman (median age 54 years, male to female ratio 1:3). [1] [3]: 122–3 This drug eruption usually occurs between the third and tenth days of therapy with warfarin derivatives. [1]
Methylene blue is employed as a medication for the treatment of methemoglobinemia, which can arise from ingestion of certain pharmaceuticals, toxins, or broad beans in those susceptible. [11] Normally, through the NADH - or NADPH -dependent methemoglobin reductase enzymes, methemoglobin is reduced back to hemoglobin.
Strychnine, when inhaled, swallowed, or absorbed through the eyes or mouth, causes poisoning which results in muscular convulsions and eventually death through asphyxia. [8] While it is no longer used medicinally, it was used historically in small doses to strengthen muscle contractions, such as a heart [ 9 ] and bowel stimulant [ 10 ] and ...
Tecarfarin is a vitamin K antagonist under development for use as an anticoagulant. [2] A Phase II/III clinical trial in 607 people, comparing it to the established vitamin K antagonist warfarin, found no difference in quality of anticoagulation or side effects between the two drugs in the overall population. [3]