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Kidney toxicity [5] associated with kidney failure; associated with development of cancer, particularly of the urinary tract, known carcinogen [8] [9] Atractylate Atractylis gummifera: Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10]
The Lifespan Extension Advocacy Foundation (LEAF) also known as Lifespan.io is a non-profit organization with mission to support fundamental research on the main mechanisms of aging and age-related diseases and educate the public on the possibility of bringing aging under medical control in order to prevent, postpone and cure age-related diseases.
A glomerular filtration rate (GFR) ≥ 60 mL/min/1.73 m 2 is considered normal without chronic kidney disease if there is no kidney damage present. Kidney damage is defined as signs of damage seen in blood, urine, or imaging studies which include lab albumin/creatinine ratio (ACR) ≥ 30. [ 62 ]
A 2018 Cochrane review of studies on men over 60 with moderate to severe lower urinary tract symptoms analyzed the impacts of phosphodiesterase inhibitors (PDE) in comparison to other drugs. [90] These drugs may improve urinary symptoms slightly and reduce urinary bother but may also cause more side effects than placebo.
Other patients may develop a shock-like condition and may require admission to a hospital. Serious complications of untreated urinary retention include bladder damage and chronic kidney failure. [4] Urinary retention is a disorder treated in a hospital, and the quicker one seeks treatment, the fewer the complications. [citation needed]
Prevalence increases with age. The prevalence of nocturia in older men is about 78%. Older men have a higher incidence of LUTS than older women. [25] Around one third of men will develop urinary tract (outflow) symptoms, of which the principal underlying cause is benign prostatic hyperplasia. [26]
Many people with this disease are unable to maintain employment due to the debilitating pain. [citation needed] Unpublished research by Dr. Ahmed Ghanem (who has cared for well over 100 women with LPHS found that untreated Symptomatic Nephroptosis - SN (Hypermobile kidney) can lead to LPHS. Nephropexy can help to relieve symptoms.
Bladder symptoms affect women of all ages. However, bladder problems are most prevalent among older women. [80] Women over the age of 60 years are twice as likely as men to experience incontinence; one in three women over the age of 60 years are estimated to have bladder control problems. [74]
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