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  2. Dupuytren's contracture - Wikipedia

    en.wikipedia.org/wiki/Dupuytren's_contracture

    In Dupuytren's contracture, the palmar fascia within the hand becomes abnormally thick, which can cause the fingers to curl and can impair finger function. The main function of the palmar fascia is to increase grip strength; thus, over time, Dupuytren's contracture decreases a person's ability to hold objects and use the hand in many different ...

  3. Collagenase clostridium histolyticum - Wikipedia

    en.wikipedia.org/wiki/Collagenase_clostridium...

    Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen.It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous ...

  4. Acquired hand deformity - Wikipedia

    en.wikipedia.org/wiki/Acquired_hand_deformity

    Osteoarthritis in the left hand index finger of an affected patient. Dupuytren's contracture is characterised by the thickening and tightening of fibrous tissue layers in the palm. [3] However, the causes of this progressive condition remain unknown. [3]

  5. Muscle contracture - Wikipedia

    en.wikipedia.org/wiki/Muscle_contracture

    In adjunct with surgery, refractory muscle contracture can also be treated with Botulinum toxins A and B; however, the effectiveness of the toxin is slowly lost over time, and most patients need a single treatment to correct muscle contracture over the first few weeks after surgery. [21] Shortening of the surgically lengthened muscle can re-occur.

  6. Guillaume Dupuytren - Wikipedia

    en.wikipedia.org/wiki/Guillaume_Dupuytren

    Guillaume Dupuytren, Baron Dupuytren (UK: / ˌ dj uː p w iː ˈ t r æ̃, dj uː ˈ p w iː t r ɛ n /, [1] US: / d ə p w iː ˈ t r æ̃, d ə ˈ p w iː t r ən /, [2] French: [ɡijom dypɥitʁɛ̃]; 5 October 1777 – 8 February 1835) was a French anatomist and military surgeon.

  7. Hand injury - Wikipedia

    en.wikipedia.org/wiki/Hand_injury

    The pain frequently occurs at night and can even radiate to the shoulder. Even though the diagnosis is straightforward, the treatment is surgical decompression of the median nerve after deroofing of the carpal tunnel. [3] Dupuytren's contracture is another disorder of the fingers that is due to thickening of the underlying skin tissues of the ...

  8. Contracture - Wikipedia

    en.wikipedia.org/wiki/Contracture

    In pathology, a contracture is a shortening of muscles, tendons, skin, and nearby soft tissues that causes the joints to shorten and become very stiff, preventing normal movement. [ 1 ] [ 2 ] A contracture is usually permanent, but less commonly can be temporary (such as in McArdle disease ), [ 3 ] or resolve over time but reoccur later in life ...

  9. Plantar fibromatosis - Wikipedia

    en.wikipedia.org/wiki/Plantar_fibromatosis

    [3] [4] A similar disease is Dupuytren's disease, which affects the hand and causes bent hand or fingers. As in most forms of fibromatosis, it is usually benign and its onset varies with each patient. [5] The nodules are typically slow-growing [2] [5] and most often found in the central and medial portions of the plantar fascia. [2]

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