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In eukaryote cells, RNA polymerase III (also called Pol III) is a protein that transcribes DNA to synthesize 5S ribosomal RNA, tRNA, and other small RNAs. The genes transcribed by RNA Pol III fall in the category of "housekeeping" genes whose expression is required in all cell types and most environmental conditions.
74414 Ensembl ENSG00000186141 ENSMUSG00000028099 UniProt Q9BUI4 Q9D483 RefSeq (mRNA) NM_001303456 NM_006468 NM_028925 RefSeq (protein) NP_001290385 NP_006459 NP_083201 Location (UCSC) Chr 1: 145.82 – 145.84 Mb Chr 3: 96.62 – 96.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse DNA-directed RNA polymerase III subunit RPC3 is an enzyme that in humans is encoded by the POLR3C gene ...
70408 Ensembl ENSG00000132664 ENSMUSG00000027427 UniProt Q9H1D9 Q921X6 RefSeq (mRNA) NM_001282526 NM_006466 NM_029763 NM_027417 RefSeq (protein) NP_001269455 NP_006457 NP_084039 Location (UCSC) Chr 20: 18.47 – 18.48 Mb Chr 2: 144.37 – 144.38 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse DNA-directed RNA polymerase III subunit RPC6 is an enzyme that in humans is encoded by the ...
The paused transcribing complex has two options: (1) release the nascent transcript and begin anew at the promoter or (2) reestablish a new 3′-OH on the nascent transcript at the active site via RNA polymerase's catalytic activity and recommence DNA scrunching to achieve promoter escape.
The lambda gene N, codes for an antitermination protein (pN) that is necessary to allow RNA polymerase to read through the terminators located at the ends of the immediate early genes. Another antitermination protein, pQ, is required later in phage infection. pN and pQ act on RNA polymerase as it passes specific sites.
Repressor of RNA polymerase III transcription MAF1 homolog is a protein that in humans is encoded by the MAF1 gene. [5] [6] [7] This gene encodes a protein that is homologous to Maf1, a Saccharomyces cerevisiae protein which is highly conserved in eukaryotic cells. S. cerevisiae Maf1 is a negative effector of RNA polymerase III (Pol III). It ...
Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells. The length of an average snRNA is approximately 150 nucleotides. They are transcribed by either RNA polymerase II or RNA polymerase III. [1]
A study conducted in 2018 screened patients with wheat related disorders for 10 anti-ENA antibodies. SSA (Ro) SSB (La) RNP/Sm; Jo-1; Sm; Scl-70; Chromatin; Centromere; Histone; RNA polymerase III; 73% of celiac disease subjects tested positive for anti-histone and was the most prevalent, which is typically associated with drug-induced lupus ...