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  2. Bicyclic molecule - Wikipedia

    en.wikipedia.org/wiki/Bicyclic_molecule

    The numbers are sometimes omitted in unambiguous cases. For example, bicyclo[1.1.0]butane is typically called simply bicyclobutane. The heterocyclic molecule DABCO has a total of 8 atoms in its bridged structure, hence the root name octane. Here the two bridgehead atoms are nitrogen instead of carbon atoms.

  3. Bicyclobutane - Wikipedia

    en.wikipedia.org/wiki/Bicyclobutane

    The intermediate 1-bromo-3-chlorocyclobutane can also be prepared via a modified Hunsdiecker reaction from 3-chlorocyclobutanecarboxylic acid using mercuric oxide and bromine: [4] A synthetic approach to bicyclobutane derivatives involves ring closure of a suitably substituted 2-bromo-1-(chloromethyl)cyclopropane with magnesium in THF. [5]

  4. Cyclobutane - Wikipedia

    en.wikipedia.org/wiki/Cyclobutane

    Cyclobutane is a cycloalkane and organic compound with the formula (CH 2) 4.Cyclobutane is a colourless gas and is commercially available as a liquefied gas.Derivatives of cyclobutane are called cyclobutanes.

  5. Intermediate agricultural product - Wikipedia

    en.wikipedia.org/wiki/Intermediate_agricultural...

    Applied to trade policy, intermediate products are one of three categories of agricultural products used by the Foreign Agricultural Service to report export and import data under its BICO system (the others are bulk and consumer-oriented agricultural products).

  6. Reaction intermediate - Wikipedia

    en.wikipedia.org/wiki/Reaction_intermediate

    In chemistry, a reaction intermediate, or intermediate, is a molecular entity arising within the sequence of a stepwise chemical reaction. It is formed as the reaction product of an elementary step, from the reactants and/or preceding intermediates, but is consumed in a later step. It does not appear in the chemical equation for the overall ...

  7. Cyclobutanecarboxylic acid - Wikipedia

    en.wikipedia.org/wiki/Cyclobutanecarboxylic_acid

    Cyclobutanecarboxylic acid is an intermediate in organic synthesis. For example, it is a precursor to cyclobutylamine. For example, it is a precursor to cyclobutylamine. [ 3 ]

  8. Reactive intermediate - Wikipedia

    en.wikipedia.org/wiki/Reactive_intermediate

    In chemistry, a reactive intermediate or an intermediate is a short-lived, high-energy, highly reactive molecule. When generated in a chemical reaction, it will quickly convert into a more stable molecule. Only in exceptional cases can these compounds be isolated and stored, e.g. low temperatures, matrix isolation. When their existence is ...

  9. Drug Master File - Wikipedia

    en.wikipedia.org/wiki/Drug_Master_File

    In the United States, DMFs are submitted to the Food and Drug Administration (FDA). The Main Objective of the DMF is to support regulatory requirements and to prove the quality, safety and efficacy of the medicinal product for obtaining an Investigational New Drug Application (IND), a New Drug Application (NDA),As an Abbreviated New Drug Application (ANDA), another DMF, or an Export Application.