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Adenomyosis is a medical condition characterized by the growth of cells that proliferate on the inside of the uterus (endometrium) atypically located among the cells of the uterine wall , [2] as a result, thickening of the uterus occurs. As well as being misplaced in patients with this condition, endometrial tissue is completely functional.
Metformin, a biguanide, is a common insulin sensitizer often given to treat women with PCOS. [10] No other insulin sensitizers have evidence of effective and safe use of fertility treatment. [ 10 ] Previously, metformin was recommended as treatment for anovulation in polycystic ovary syndrome , but in the largest trial to date, comparing ...
Patients with adenomyosis have been found to have lower successful live birth rates and higher rates of miscarriage following in vitro fertilization (IVF) compared to those without adenomyosis. [ 2 ] [ 7 ] Multiple studies have investigated the impact of GnRH agonist therapy on in vitro fertilization success in patients with adenomyosis.
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A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones. [1] They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of hormone-sensitive cancers such as prostate cancer and breast cancer, certain gynecological disorders like heavy periods and endometriosis ...
In rare cases, oophorectomy can be used to treat endometriosis by eliminating the menstrual cycle, which will reduce or eliminate the spread of existing endometriosis as well as reducing pain. Since endometriosis results from an overgrowth of the uterine lining, removal of the ovaries as a treatment for endometriosis is often done in ...
Danazol is used primarily in the treatment of endometriosis.It has also been used – mostly off-label – for other indications, namely in the management of menorrhagia, fibrocystic breast disease, immune thrombocytopenic purpura, premenstrual syndrome, breast pain, and hereditary angioedema. [20]
When a woman's natural cycle is monitored to collect a naturally selected ovum (egg) for fertilisation, it is known as natural cycle IVF. The fertilised egg ( zygote ) is then transferred to the patient's uterus with the intention of establishing a successful pregnancy.