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Periorbital cellulitis, or preseptal cellulitis, is an inflammation and infection of the eyelid and portions of skin around the eye anterior to the orbital septum. [1] It may be caused by breaks in the skin around the eye, and subsequent spread to the eyelid; infection of the sinuses around the nose (); or from spread of an infection elsewhere through the blood.
Orbital septum acts as a physical barrier that prevents the infection of the anterior part of the eye spreading posteriorly. For example, preseptal cellulitis mainly infects the eyelids, anterior to the orbital septum. Meanwhile, orbital cellulitis is located posterior the orbital septum, due to infections spreading from the ethmoidal sinuses.
Orbital cellulitis is inflammation of eye tissues behind the orbital septum. It is most commonly caused by an acute spread of infection into the eye socket from either the adjacent sinuses or through the blood. It may also occur after trauma. When it affects the rear of the eye, it is known as retro-orbital cellulitis.
Cellulitis symptoms and signs. When you have cellulitis, an area of your skin — often on one of your legs — becomes red, swollen, warm and possibly painful. Causes of cellulitis.
Cellulitis in 2015 resulted in about 16,900 deaths worldwide, up from 12,600 in 2005. [8] Cellulitis is a common global health burden, with more than 650,000 admissions per year in the United States alone. In the United States, an estimated 14.5 million cases annually of cellulitis account for $3.7 billion in ambulatory care costs alone.
The septal veins drain blood from the septum pellucidum bilaterally [2] and terminate at the venous angle formed with the thalamostriate veins. [4] Research by Jonathan Roth et al., 2010, has shown that the septal veins are often asymmetrical. [5]
In contrast to cellulitis, erysipelas is a bacterial infection involving the more superficial layers of the skin, present with an area of redness with well-defined edges, and more often is associated with a fever.
The structure of this tissue is composed of septal (i.e. linear strands) and lobular compartments, which differ in microscopic appearance. [8] Functionally, the subcutaneous fat insulates the body, absorbs trauma, and serves as a reserve energy source. [14]