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Neurotrophin-3, or NT-3, is a neurotrophic factor, in the NGF-family of neurotrophins. It is a protein growth factor that has activity on certain neurons of the peripheral and central nervous system ; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses .
Recent research has suggested a number of roles for the LNGFR, including in development of the eyes and sensory neurons, [20] [21] and in repair of muscle and nerve damage in adults. [ 22 ] [ 23 ] [ 24 ] Two distinct subpopulations of Olfactory ensheathing glia have been identified [ 25 ] with high or low cell surface expression of low-affinity ...
4803 18049 Ensembl ENSG00000134259 ENSMUSG00000027859 UniProt P01138 P01139 RefSeq (mRNA) NM_002506 NM_001112698 NM_013609 RefSeq (protein) NP_002497 NP_001106168 NP_038637 Location (UCSC) Chr 1: 115.29 – 115.34 Mb Chr 3: 102.38 – 102.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the ...
Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. [ 5 ] [ 6 ] The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins .
Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [7] [8] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5.
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Neurotrophin-4 (NT-4), [5] also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene. [6] It is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. [7] [8] NT-4 was first discovered and isolated from xenopus and viper in the year 1991 by Finn Hallbook et.al [9]
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