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Insulin aspart, sold under the brand name NovoLog, among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [17] It is generally used by injection under the skin but may also be used by injection into a vein . [ 17 ]
The company makes several drugs under various brand names, including Levemir, Tresiba, NovoLog, Novolin R, NovoSeven, NovoEight, and Victoza. [1] Novo Nordisk employs more than 48,000 people globally, and markets its products in 168 countries. [7]
The parameters of the dose response curve reflect measures of potency (such as EC50, IC50, ED50, etc.) and measures of efficacy (such as tissue, cell or population response). A commonly used dose–response curve is the EC 50 curve, the half maximal effective concentration, where the EC 50 point is defined as the inflection point of the curve.
The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.
In medical imaging, a time-activity curve is a curve of radioactivity (in terms of concentration) plotted on the y-axis against the time plotted on the x-axis. It shows the concentration of a radiotracer within a region of interest in an image, measured over time from a dynamic scan.
The strength-duration curve is a plot of the threshold current (I) versus pulse duration (d) required to stimulate excitable tissue. [4] As mentioned, the two important points on the curve are rheobase (b) and chronaxie (c), which correlates to twice the rheobase (2b). Strength-duration curves are useful in studies where the current required is ...
Note that the amplitude and the exact shape of the action potential can vary according to the exact experimental technique used for acquiring the signal. Biological neuron models , also known as spiking neuron models , [ 1 ] are mathematical descriptions of the conduction of electrical signals in neurons .
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