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In the liver, it is the type of fatty acid, not the quantity, that determines the extent of the lipotoxic effects. In hepatocytes, the ratio of monounsaturated fatty acids and saturated fatty acids leads to apoptosis and liver damage. There are several potential mechanisms by which the excess fatty acids can cause cell death and damage.
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
Primary sclerosing cholangitis and primary biliary cholangitis are distinct entities and exhibit important differences, including the site of tissue damage within the liver, associations with IBD, which includes ulcerative colitis and Crohn's disease, response to treatment, and risks of disease progression.
The discovery could help doctors better diagnose liver-related disease and determine appropriate treatment options, said Dr. Anna Mae Diehl, a hepatologist and a professor of medicine at Duke.
Herbal supplements are going viral on TikTok due to their reported health benefits, but new research finds six of the most popular (including green tea extract and turmeric) have been linked with ...
Dr. Clarke notes that mild liver damage usually starts with loss of appetite and fatigue, while more acute or severe liver damage has other symptoms. If you ever notice that you have jaundice, see ...
Lies of P (Korean: P의 거짓) is a 2023 action role-playing game developed by Neowiz Games and Round8 Studio and published by Neowiz. Loosely based on Carlo Collodi's 1883 novel, The Adventures of Pinocchio, the story follows the titular puppet traversing the fictional city of Krat, plagued by both an epidemic of petrification disease and a puppet uprising.
Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [1] [2] [3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis.