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First-line treatment of alcoholic hepatitis is treatment of alcoholism. [36] For those who abstain completely from alcohol , reversal of liver disease and a longer life are possible; patients at every disease stage have been shown to benefit by prevention of additional liver injury.
autoimmune hepatitis type II and chronic hepatitis C (10%) anti-LKM 2: cytochrome P450 2C9: drug-induced hepatitis (tienilic acid–induced) anti-LKM 3: cytochrome P450 1A2: chronic active hepatitis in association with autoimmune polyendocrine syndrome type 1; [1] hepatitis D
Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria, [1] primarily the mitochondria in cells of the liver.. The presence of AMA in the blood or serum of a person may be indicative of the presence of, or the potential to develop, the autoimmune disease primary biliary cholangitis (PBC; previously known as primary biliary cirrhosis).
Without treatment, the ten-year survival rate for individuals with symptomatic autoimmune hepatitis is 50%. However, with treatment, the ten-year survival rate is above 90%. Despite the benefits of treatment, people with autoimmune hepatitis generally have a lower transplant-free survival than the general population.
Viral hepatitis is liver inflammation due to a viral infection. [1] [2] It may present in acute form as a recent infection with relatively rapid onset, or in chronic form, typically progressing from a long-lasting asymptomatic condition up to a decompensated hepatic disease and hepatocellular carcinoma (HCC).
Recommend adding histologic images to the histology sub-section Treatment- My favorite part of the article! I really enjoyed reading about current treatment options, along with the future direction of treatment. Citations high quality and appropriately sourced. Recommend adding images of liver biopsy findings.
For example, convalescent serum, passive antibody transfusion from a previous human survivor, used to be the only known effective treatment for ebola infection with a high success rate of 7 out of 8 patients surviving. [1] Antisera are widely used in diagnostic virology laboratories.
Patients who developed antibodies against HBsAg (anti-HBsAg seroconversion) are usually considered non-infectious. HBsAg detection by immunoassay is used in blood screening, to establish a diagnosis of hepatitis B infection in the clinical setting (in combination with other disease markers) and to monitor antiviral treatment.