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It should not be used in any patient with liver disease or a history of liver disease, and doctors should be monitoring their patients for early signs of liver problems. The use of diacerein is to be limited to treating symptoms of osteoarthritis affecting the hip or knee. Diacerein should not be administered during pregnancy and lactation.
Pain is generally just below the kneecap. [2] Symptoms may worsen if the knee is overly straightened or bent for too long a period. [2] Complications may include an inability to fully straighten the knee. [2] The underlying mechanism may involve bleeding, inflammation, or insufficient space for the fat pad. [2]
Liver problems in people with rheumatoid arthritis may be due to the underlying disease process or as a result of the medications used to treat the disease. [39] A coexisting autoimmune liver disease, such as primary biliary cirrhosis or autoimmune hepatitis may also cause problems.
Sitting for extended periods can cause stiffness in your knees and reduce circulation, which can lead to more pain. Additionally, knee pain might stem from your back or hips, even if you don’t ...
During a gout flare-up, you have acute gout symptoms, such as intense pain and swelling in an affected joint. Intercritical gout. This is the time between gout flares when you have no symptoms ...
Running long distance can cause pain to the knee joint, as it is a high-impact exercise. [2] The location and severity of knee pain may vary, depending on the cause of the problem. Signs and symptoms that sometimes accompany knee pain include: [1] Swelling and stiffness; Redness and warmth to the touch; Weakness or instability; Popping or ...
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