Search results
Results from the WOW.Com Content Network
A lethal infection in mink, the Aleutian disease virus lies dormant in ferrets until stress or injury allows it to surface. While the parvovirus itself causes little or no harm to the ferret host, the large number of antibodies produced in response to the presence of the virus results in a systemic vasculitis, resulting in eventual renal failure, bone marrow suppression and death. [10]
Mink enteritis virus (MEV) is a strain of Carnivore protoparvovirus 1 [1] that infects mink and causes enteritis. Like all parvoviruses, it is a small (18–26 nm), spherical virus, and has a single-stranded DNA genome. The signs and symptoms of enteritis usually appear within 4–7 days after infection.
In the past nucleic acid tests have mainly been used as a secondary test to confirm positive serological results. [3] However, as they become cheaper and more automated, they are increasingly becoming the primary tool for diagnostics and can also be use for monitoring of treatment of viral infected individuals t.
This hypothesis postulates that a yet undiscovered infectious viral agent is the cause of the disease. Although this was once the leading hypothesis, it is now a minority view. Evidence for this hypothesis is as follows: Brain particle titers purified of PrP retain infectivity. [28] Brain titers exposed to nucleases reduced infectivity by >=99% ...
Specificity indicates how well-targeted the test is to the virus in question. Highly specific tests pick up only the virus in question. Non-selective tests pick up other viruses as well. A 90% specific test will correctly identify 90% of those who are uninfected, leaving 10% with a false positive result. [13]
Cluster 5 is a designation used by the Danish Statens Serum Institut for a virus variant described by the institute in autumn 2020, in connection with investigations of SARS-CoV-2 infection among mink and humans in the north of Jutland, Denmark.
In November 2020, in Denmark, the government mandated the slaughter of all the country's 17 million mink due to reports that a mutated SARS-CoV-2 virus was being passed from mink to humans via mink farms, and that at least 12 human infections had been discovered in North Jutland.
The NS gene encodes the non-structural (NS) protein NS1, which is the replication initiator protein, and the VP gene encodes the viral protein (VP) that the viral capsid is made of. NS1 contains an HUH superfamily endonuclease domain near its N-terminus , containing both site-specific binding activity and site-specific nicking activity, and a ...