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  2. Edaravone - Wikipedia

    en.wikipedia.org/wiki/Edaravone

    In May 2017, I.V. edaravone was approved by the FDA to treat people with amyotrophic lateral sclerosis (ALS) in the United States. [13] The FDA approval was conditioned on Mitsubishi Tanabe completing several additional studies to clarify the risks of cancer and liver disease, among other effects of the medication. [14] [15]

  3. Tofersen - Wikipedia

    en.wikipedia.org/wiki/Tofersen

    Tofersen, sold under the brand name Qalsody, is a medication used for the treatment of amyotrophic lateral sclerosis (ALS). [2] Tofersen is an antisense oligonucleotide that targets the production of superoxide dismutase 1, an enzyme whose mutant form is commonly associated with amyotrophic lateral sclerosis.

  4. Sodium phenylbutyrate/ursodoxicoltaurine - Wikipedia

    en.wikipedia.org/wiki/Sodium_phenylbutyrate/urso...

    The combination was approved for medical use in Canada as Albrioza, in June 2022, [1] [2] [8] and in the United States, as Relyvrio, in September 2022. [ 5 ] [ 9 ] [ 7 ] The European Union 's drug regulators refused to approve it, citing concerns about effectiveness. [ 10 ]

  5. Amylyx's approved ALS drug flunks crucial test, shares dive - AOL

    www.aol.com/news/amylyxs-als-drug-fails-stage...

    The drug, branded as Relyvrio and the company's only product in market, was approved in September 2022 based on mid-stage trial data in 137 patients that showed the treatment slowed disease ...

  6. Denali-Sanofi's ALS drug fails to meet mid-stage trial goal - AOL

    www.aol.com/news/denali-sanofis-als-drug-fails...

    The U.S. FDA has given traditional approval for three drugs — Japanese firm Mitsubishi Tanabe's Radicava, generic drug Riluzole and Amylyx Pharmaceut Denali-Sanofi's ALS drug fails to meet mid ...

  7. What to Know About Relyvrio, the Controversial New FDA ... - AOL

    www.aol.com/know-relyvrio-controversial-fda...

    The FDA recently approved Relyvrio, a drug to treat ALS, but the agency also concluded that it’s hard to say if it actually works. The FDA recently approved Relyvrio, a drug to treat ALS, but ...

  8. Riluzole - Wikipedia

    en.wikipedia.org/wiki/Riluzole

    Riluzole was approved in the United States for the treatment of ALS by the U.S. Food and Drug Administration (FDA) in 1995. [6] A Cochrane Library review states a 9% gain in the probability of surviving one year. [5]

  9. ALS drug will be pulled from US market after study showed ...

    www.aol.com/news/als-drug-pulled-us-market...

    The Food and Drug Administration approved the much-debated drug, Relyvrio, in September 2022, following a years-long advocacy campaign by patients with amyotrophic lateral sclerosis, or ALS.

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