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In broad usage, the "practical clinical significance" answers the question, how effective is the intervention or treatment, or how much change does the treatment cause. In terms of testing clinical treatments, practical significance optimally yields quantified information about the importance of a finding, using metrics such as effect size, number needed to treat (NNT), and preventive fraction ...
Medication that have label indications mean that they were approved by the FDA. This means that they are clinically significant for the indication and manufacturers are allowed to market their drug for the indication. [2] A drug can have more than one FDA labeled indication, which means that it can be used for multiple medical conditions. [5]
A complication in medicine, or medical complication, is an unfavorable result of a disease, health condition, or treatment.Complications may adversely affect the prognosis, or outcome, of a disease.
In pharmaceuticals, an adverse event (AE) is any unexpected or harmful medical occurrence that happens to a patient during medical treatment or a clinical trial. Unlike direct side effects, an adverse event does not necessarily mean the medication directly caused the problem.
Physiological relevance is a critical factor in biomedical research because it helps to bridge the gap between basic science and clinical application. Researchers aim to design studies that not only yield statistically significant results but also have direct implications for understanding human health and disease. [1]
Clinical research is a branch of medical research that involves people and aims to determine the effectiveness and safety of medications, devices, diagnostic ...
Clinical supervision is used in many disciplines in the British National Health Service.Registered allied health professionals such as occupational therapists, [23] physiotherapists, [24] dieticians, [25] speech and language therapists [26] and art, [27] music and drama therapists are now expected to have regular clinical supervision.
Comorbidity is often referred to as multimorbidity even though the two are considered distinct clinical scenarios. [ 6 ] [ 7 ] [ 8 ] Comorbidity means that one 'index' condition is the focus of attention, and others are viewed in relation to this.