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  2. Hypothalamic–pituitary–adrenal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Schematic of the HPA axis (CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone) Hypothalamus, pituitary gland, and adrenal cortex The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a ...

  3. List of regions in the human brain - Wikipedia

    en.wikipedia.org/wiki/List_of_regions_in_the...

    3.1.4 Hypothalamus (limbic system) (HPA axis) 3.1.5 Subthalamus (HPA axis) 3.1.6 Pituitary gland ... Most famous parts of the brain highlighted in different colours.

  4. Hypothalamic–pituitary hormone - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    They can be classified as a hypothalamic–pituitary axis (HP axis) of which the adrenal (HPA Tooltip hypothalamic–pituitary–adrenal axis), gonadal (HPG Tooltip hypothalamic–pituitary–gonadal axis), thyroid (HPT Tooltip hypothalamic–pituitary–thyroid axis), somatotropic (HPS Tooltip hypothalamic–pituitary–somatotropic axis), and ...

  5. Hypothalamus - Wikipedia

    en.wikipedia.org/wiki/Hypothalamus

    In the hypothalamic–adenohypophyseal axis, releasing hormones, also known as hypophysiotropic or hypothalamic hormones, are released from the median eminence, a prolongation of the hypothalamus, into the hypophyseal portal system, which carries them to the anterior pituitary where they exert their regulatory functions on the secretion of ...

  6. Psychoneuroimmunology - Wikipedia

    en.wikipedia.org/wiki/Psychoneuroimmunology

    The immune system and the brain communicate through signaling pathways. The brain and the immune system are the two major adaptive systems of the body. Two major pathways are involved in this cross-talk: the Hypothalamic-pituitary-adrenal axis (HPA axis), and the sympathetic nervous system (SNS), via the sympathetic-adrenal-medullary axis (SAM ...

  7. Corticotropin-releasing hormone - Wikipedia

    en.wikipedia.org/wiki/Corticotropin-releasing...

    It is believed that chronic stress enhances the negative feedback inhibition of the HPA axis, resulting in lower CRH levels and HPA function. [10] [11] [12] Abnormally high levels of CRH have been found in people with major depression, [13] [6] and in the cerebrospinal fluid of people who have committed suicide. [14]

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  9. Stress (biology) - Wikipedia

    en.wikipedia.org/wiki/Stress_(biology)

    The HPA axis ultimately results in the release of cortisol, which generally has immunosuppressive effects. However, the effect of stress on the immune system is disputed, and various models have been proposed in an attempt to account for both the supposedly "immunodeficiency" linked diseases and diseases involving hyper activation of the immune ...