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  2. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Loop diuretics usually have a ceiling effect whereby doses greater than a certain maximum amount will not increase the clinical effect of the drug. Also, there is a threshold minimum concentration of loop diuretics that needs to be achieved at the thick ascending limb to enable the onset of abrupt diuresis.

  3. Ototoxicity - Wikipedia

    en.wikipedia.org/wiki/Ototoxicity

    Loop and thiazide diuretics carry this side effect. The loop diuretic furosemide is associated with ototoxicity, particularly when doses exceed 240 mg per hour. [21] The related compound ethacrynic acid has a higher association with ototoxicity, and is therefore used only in patients with sulfa allergies. Diuretics are thought to alter the ...

  4. Ototoxic medication - Wikipedia

    en.wikipedia.org/wiki/Ototoxic_medication

    Loop diuretics is a major class of diuretic drugs indicated for oedema due to heart failure, liver disease and kidney disease. It is also used for treating hypertension. [26] Common examples include furosemide, bumetanide and ethacrynic acid. Loop diuretics act on the thick ascending limb of the loop of Henle in the kidney nephrons.

  5. Semaglutide may improve heart failure symptoms, reduce need ...

    www.aol.com/semaglutide-may-improve-heart...

    New research reports that semaglutide reduces the need and dose of loop diuretics in people with heart failure with preserved ejection fraction (HFpEF). The findings show semaglutide also improved ...

  6. Daily low-dose aspirin has its benefits — and risks. Here's ...

    www.aol.com/lifestyle/aspirin-every-day-why-not...

    Based on all of that, the USPSTF concluded that taking a daily aspirin can increase the risk of having major gastrointestinal bleeding by up to 60% and brain bleeding up to 30%.

  7. Diuretic - Wikipedia

    en.wikipedia.org/wiki/Diuretic

    Loop diuretics, such as furosemide, inhibit the body's ability to reabsorb sodium at the ascending loop in the nephron, which leads to an excretion of water in the urine, whereas water normally follows sodium back into the extracellular fluid. Other examples of high-ceiling loop diuretics include ethacrynic acid and torasemide. [citation needed]

  8. Furosemide - Wikipedia

    en.wikipedia.org/wiki/Furosemide

    Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. [4] Furosemide may also be used for the treatment of high blood pressure. [4] It can be taken intravenously or orally. [4]

  9. Metabolic alkalosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_alkalosis

    Diuretic therapy – loop diuretics and thiazides can both initially cause increase in chloride, but once stores are depleted, urine excretion will be below < 25 mEq/L. The loss of fluid from sodium excretion causes a contraction alkalosis. Diuretic abuse among athletes [4] and people with eating disorders [5] may present with metabolic alkalosis.

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