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  2. Management of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Parkinson's...

    In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...

  3. Convection enhanced delivery - Wikipedia

    en.wikipedia.org/wiki/Convection_enhanced_delivery

    GDNF is known to protect neurons which produce dopamine. Parkinson's disease has been shown to decrease the amount of dopamine which can be produced in the brain, so researchers hope to be able to decrease the side effects of Parkinson's disease by protecting neurons which produce dopamine.

  4. Cell-based therapies for Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Cell-based_Therapies_for...

    The first cell-based therapy investigated for Parkinson's disease utilized the adrenal medulla. The adrenal medulla is the innermost part of the adrenal gland and contains neural crest derived chromaffin cells which secrete norepinephrine , epinephrine and to a far lesser extent dopamine into the blood.

  5. Substantia nigra - Wikipedia

    en.wikipedia.org/wiki/Substantia_nigra

    Levodopa can cross the blood–brain barrier and increases dopamine levels in the substantia nigra, thus alleviating the symptoms of Parkinson's disease. The drawback of levodopa treatment is that it treats the symptoms of Parkinson's (low dopamine levels), rather than the cause (the death of dopaminergic neurons in the substantia nigra).

  6. Dopamine therapy - Wikipedia

    en.wikipedia.org/wiki/Dopamine_therapy

    One dopamine precursor, Levodopa, was the first drug approved specifically for Parkinson's disease. [2] DRT increases dopamine in the brain to optimal levels in order to return motor skills, impulsivity, and decision making to normal function. [3] Although DRT can improve motor skills and decision making in patients with mild to severe ...

  7. Aromatic L-amino acid decarboxylase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatic_L-amino_acid_de...

    It is used to inhibit the decarboxylation of L-DOPA to dopamine outside the brain, i.e. in the blood. This is primarily co-administered with L -DOPA to combat Parkinson's disease . Administration can prevent common side-effects, such as nausea and vomiting, as a result of interaction with D 2 receptors in the vomiting center (or cheomoreceptor ...

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