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  2. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    However, food has been found to substantially delay the absorption of pregabalin and to significantly reduce peak levels without affecting the bioavailability of the drug; T max values for pregabalin of 0.6 hours in a fasted state and 3.2 hours in a fed state (5-fold difference), and the C max is reduced by 25–31% in a fed versus fasted state ...

  3. Pregabalin - Wikipedia

    en.wikipedia.org/wiki/Pregabalin

    Pregabalin is a GABA analogue that is a 3-substituted derivative as well as a γ-amino acid. [19] [29] Because of its chemical and pharmacological similarities to gabapentin, it is sometimes called a gabapentinoid drug. Specifically, pregabalin is (S)-(+)-3-isobutyl-GABA.

  4. Apoquel for Cats: Uses, Dosage, & Side Effects - AOL

    www.aol.com/lifestyle/apoquel-cats-uses-dosage...

    However, since its introduction to the market in 2013, the drug’s efficacy in cats has been subject to extensive study. The post Apoquel for Cats: Uses, Dosage, & Side Effects appeared first on ...

  5. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Parke-Davis developed a drug called pregabalin, which is related in structure to gabapentin, as a successor to gabapentin. [159] Another similar drug atagabalin has been unsuccessfully tried by Pfizer as a treatment for insomnia. [160] A prodrug form (gabapentin enacarbil) [161] was approved by the U.S. Food and Drug Administration (FDA).

  6. Feline hyperesthesia syndrome - Wikipedia

    en.wikipedia.org/wiki/Feline_hyperesthesia_syndrome

    Around 9–12 months, or when the cat reaches maturity. Duration: The syndrome will remain present for the cat's entire life, but episodes only last for one to two minutes. Treatment: Behavioural adaptation, pharmaceuticals and alternative medicine. Prognosis: Good, provided the cat doesn't self-mutilate excessively.

  7. Calcium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker

    Gabapentinoids, such as gabapentin and pregabalin, bind selectively to the α 2 δ protein that was first described as an integral part of voltage-gated calcium channels. These drugs do not directly block calcium channels [ 13 ] [ 14 ] but can alter the transport of functional calcium channels to the cell membrane and they also reduce the ...

  8. Analgesic - Wikipedia

    en.wikipedia.org/wiki/Analgesic

    An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and ...

  9. Vigabatrin - Wikipedia

    en.wikipedia.org/wiki/Vigabatrin

    Vigabatrin reduced cholecystokinin tetrapeptide-induced symptoms of panic disorder, in addition to elevated cortisol and ACTH levels, in healthy volunteers. [12]Vigabatrin is also used to treat seizures in succinic semialdehyde dehydrogenase deficiency (SSADHD), which is an inborn GABA metabolism defect that causes intellectual disability, hypotonia, seizures, speech disturbance, and ataxia ...