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Vancomycin is a glycopeptide antibiotic medication used to treat certain bacterial infections. [7] It is administered intravenously (injection into a vein) to treat complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. [8]
It is not effective against methicillin-resistant Staphylococcus aureus (MRSA). [7] It is taken by mouth or given by injection into a vein or muscle. [6] Common side effects include an upset stomach. [6] Other side effects may include muscle or joint pains, shortness of breath, and liver problems.
The effective treatment of MRSA with linezolid has been successful [87] in 87% of people. Linezolid is more effective in soft tissue infections than vancomycin. [89] [1] This is compared to eradication of infection in those with MRSA treated with vancomycin. Treatment with vancomycin is successful in approximately 49% of people. [1]
Dalbavancin, sold under the brand names Dalvance in the US and Xydalba in the EU (both by AbbVie) among others, is a second-generation lipoglycopeptide antibiotic medication. It belongs to the same class as vancomycin, the most widely used and one of the treatments available to people infected with methicillin-resistant Staphylococcus aureus ...
If an allergic reaction to ceftaroline occurs, the drug should be discontinued. Serious acute hypersensitivity reactions require emergency treatment with epinephrine and other emergency measures, that may include airway management, oxygen, intravenous fluids, antihistamines, corticosteroids, and vasopressors as clinically indicated.
The estimated incidence is 1 in 15,000 exposures, and is more frequent in people over 55 years old, females, and those with treatment longer than 2 weeks. [6] It should be used with caution and monitored in the elderly, particularly with intravenous administration, due to a risk of thrombophlebitis. [1]
Mupirocin, sold under the brand name Bactroban among others, is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis. [5] [6] [7] It may also be used to get rid of methicillin-resistant S. aureus (MRSA) when present in the nose without symptoms. [6]
Although many strains of MRSA remain sensitive to fusidic acid, there is a low genetic barrier to drug resistance (a single point mutation is all that is required), fusidic acid should never be used on its own to treat serious MRSA infection and should be combined with another antimicrobial such as rifampicin when administering oral or topical ...