Search results
Results from the WOW.Com Content Network
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.
Class V agents work by other or unknown mechanisms. ... Treat atrial flutter and atrial ... The prolongation of the action potential duration and refractory period ...
For example, although the class III antiarrhythmic agent ibutilide is an effective treatment for atrial flutter, rates of recurrence after treatment are quite high (70–90%). [1] Additionally, there are some specific considerations particular to treatment of atrial flutter.
There are various classes of agents that are most effective for pharmacological cardioversion. Class I agents are sodium (Na) channel blockers (which slow conduction by blocking the Na+ channel) and are divided into 3 subclasses a, b and c. Class Ia slows phase 0 depolarization in the ventricles and increases the absolute refractory period.
Harbaugh's fight is with atrial flutter, a condition where the heart's upper chambers beat faster than the lower chambers, ... Sir James Black discovered the class of drugs in 1964, according to ...
Dronedarone has been termed a "multichannel blocker". [citation needed] However, it is unclear which channel(s) play a pivotal role in its success. [9]Thus, dronedarone's actions at the cellular level are controversial, with most studies suggesting an inhibition in multiple outward potassium currents including rapid delayed rectifier, slow delayed rectifier and ACh-activated inward rectifier. [10]
Dofetilide is a class III antiarrhythmic agent. [2] It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 μg of dofetilide. It is not available in Europe [3] or Australia. [4]
Google introduced Flutter for native app development. Built using Dart, C, C++ and Skia, Flutter is an open-source, multi-platform app UI framework. Prior to Flutter 2.0, developers could only target Android, iOS and the web. Flutter 2.0 released support for macOS, Linux, and Windows as a beta feature. [67]