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Platelets collected by using apheresis at an American Red Cross donation center. Not all platelet transfusions use platelets collected by automated apheresis. The platelets can also be separated from donations of whole blood collected in a traditional blood donation, but there are several advantages to separating the platelets at the time of collection.
Blood donation pictogram Blood donation center at the University Hospital of Basel, Switzerland. From left to right: Two cell separators for apheresis, secluded office for pre-donation blood pressure measurement and blood count, and on the right, chairs for whole blood donations. A patient donating blood at a Blood Bank in Córdoba, Argentina
Post-transfusion purpura (PTP) is a delayed adverse reaction to a blood transfusion or platelet transfusion that occurs when the body has produced alloantibodies to the allogeneic transfused platelets' antigens. These alloantibodies destroy the patient's platelets leading to thrombocytopenia, a rapid decline in platelet count. [1]
Problems later in life may arise from anything that can cause internal bleeding such as: stomach ulcers, surgery, trauma, or menstruation. [2] Abnormality of the abdomen, nosebleeds , heavy menstrual bleeding , purpura , too few platelets circulating in the blood , and prolonged bleeding time have also been listed as symptoms of various giant ...
Understand the different processes before you decide to give.
For apheresis platelet donation the donor's pre platelet count should be above 150 x 10^9/L. For apheresis plasma donation, the donor's total protein level should be greater than 60 g/L. For double red cell apheresis, donors of either gender require a minimum hemoglobin level of 14.0 g/dl. [15]
A normal human platelet count ranges from 150,000 to 450,000 platelets/microliter (μL) of blood. [4] Values outside this range do not necessarily indicate disease. One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. [5]
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