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The word toxicology (/ ˌ t ɒ k s ɪ ˈ k ɒ l ə dʒ i /) is a neoclassical compound from Neo-Latin, first attested c. 1799, [3] from the combining forms toxico-+ -logy, which in turn come from the Ancient Greek words τοξικός toxikos, "poisonous", and λόγος logos, "subject matter").
The discipline of evidence-based toxicology (EBT) strives to transparently, consistently, and objectively assess available scientific evidence in order to answer questions in toxicology, [1] the study of the adverse effects of chemical, physical, or biological agents on living organisms and the environment, including the prevention and amelioration of such effects. [2]
A threshold model used in toxicology posits that anything above a certain dose of a toxin is dangerous, and anything below it safe. This model is usually applied to non-carcinogenic health hazards. Edward J. Calabrese and Linda A. Baldwin wrote: The threshold dose-response model is widely viewed as the most dominant model in toxicology. [6]
T. Tarantism; Test Methods Regulation; Thermostability; Threshold model; Threshold of toxilogical concern; Thyrotoxicosis factitia; Tissue residue; Tobacco smoke
It is an application of pharmacokinetics to determine the relationship between the systemic exposure of a compound and its toxicity.It is used primarily for establishing relationships between exposures in toxicology experiments in animals and the corresponding exposures in humans.
Toxinology is a subfield of toxicology dedicated to toxic substances produced by or occurring in living organisms. [1] [2] References This page was last edited on 23 ...
Toxicology testing, also known as safety assessment, or toxicity testing, is the process of determining the degree to which a substance of interest negatively impacts the normal biological functions of an organism, given a certain exposure duration, route of exposure, and substance concentration.
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. [1] Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity).