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The term "interstitial cystitis" was coined by Dr. Alexander Skene in 1887 to describe the disease. [13] In 2002, the United States amended the Social Security Act to include interstitial cystitis as a disability. The first guideline for diagnosis and treatment of interstitial cystitis is released by a Japanese research team in 2009. [71]
Eosinophilic cystitis is a rare type of interstitial cystitis first reported in 1960 by Edwin Brown. [1] Eosinophilic cystitis has been linked to a number of etiological factors, including allergies , bladder tumors , trauma to the bladder, parasitic infections , and chemotherapy drugs , though the exact cause of the condition is still unknown.
In relation to interstitial cystitis, when noxious stimuli are present, it causes injury to the bladder mucosa resulting in recruitment of inflammatory cells. [3] Disruption of glycosaminoglycan (GAG) layer [ 14 ] along with the increased presence of mast cells , T cells , and B cells causes the bladder epithelium to become more permeable.
Section 8 was a category of military discharge employed by the United States Armed Forces which was used for servicemembers judged mentally unfit for service. The term "Section 8" eventually came to mean any service member given such a discharge, or behaving as if deserving such a discharge, as in the expression, "he's a Section 8".
But in war, asking troops to meet the ideals and values they carry into battle – always be honorable, always be courageous, always treat civilians with respect, never harm a non-combatant – may itself cause moral injury when these ideals collide with the reality of combat. Accomplishing the mission may mean placing innocent civilians at risk.
Common causes in include: endometriosis in women, bowel adhesions, irritable bowel syndrome, and interstitial cystitis. [5] [6] The cause may also be a number of poorly understood conditions that may represent abnormal psychoneuromuscular function. The role of the nervous system in the genesis and moderation of pain is explored. [7]
It’s the same routine each time. The initial feeling of dread that something isn’t quite right down there. The familiar sensation of burning that resonates from the urethra after urinating (or ...
Patients with interstitial cystitis may find relief by modifying their diet to remove foods and beverages that trigger symptoms: caffeinated beverages, particularly coffee (regular and decaf), tea, green tea, soda, artificial sugars and fruit juices. Cranberry juice may also trigger intense pain and discomfort.