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The term "interstitial cystitis" was coined by Dr. Alexander Skene in 1887 to describe the disease. [13] In 2002, the United States amended the Social Security Act to include interstitial cystitis as a disability. The first guideline for diagnosis and treatment of interstitial cystitis is released by a Japanese research team in 2009. [71]
Eosinophilic cystitis is a rare type of interstitial cystitis first reported in 1960 by Edwin Brown. [1] Eosinophilic cystitis has been linked to a number of etiological factors, including allergies , bladder tumors , trauma to the bladder, parasitic infections , and chemotherapy drugs , though the exact cause of the condition is still unknown.
In relation to interstitial cystitis, when noxious stimuli are present, it causes injury to the bladder mucosa resulting in recruitment of inflammatory cells. [3] Disruption of glycosaminoglycan (GAG) layer [ 14 ] along with the increased presence of mast cells , T cells , and B cells causes the bladder epithelium to become more permeable.
Mar. 17—(StatePoint) Life in the U.S. Armed Forces can be challenging, especially for the youngest members of the nation's military community: the 1.6 million children of service members. From ...
Patients with interstitial cystitis may find relief by modifying their diet to remove foods and beverages that trigger symptoms: caffeinated beverages, particularly coffee (regular and decaf), tea, green tea, soda, artificial sugars and fruit juices. Cranberry juice may also trigger intense pain and discomfort.
The blast blew apart much of the adobe building. As the dust settled, the Marines could hear shouting and wailing. Their interpreter said, “They want to bring out the wounded.” And as the torn and bleeding bodies were dragged out, it became clear that the Taliban had herded women and children into the building as human shields.
Hemorrhagic cystitis, characterized by blood in the urine, can occur secondary to a number of causes including: infections, radiation therapy, underlying cancer, medications and toxins. [59] Medications that commonly cause this problem include the chemotherapeutic agent cyclophosphamide with rates of 2–40%. [ 59 ]
And from the smoke and rubble came the dying, dragging the dead: the women and children the Taliban had herded into the compound. Joseph sagged against a wall, horrified and sobbing at the sight. For Joseph, it was a classic moral injury. Firing back at the Taliban may have been a justifiable military necessity.