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  2. R-loop - Wikipedia

    en.wikipedia.org/wiki/R-loop

    Schematic representation of factors promoting R-loop formation and stabilization. An R-loop is a three-stranded nucleic acid structure, composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA. R-loops may be formed in a variety of circumstances and may be tolerated or cleared by cellular components.

  3. Structural motif - Wikipedia

    en.wikipedia.org/wiki/Structural_motif

    Depending upon the sequence and other conditions, nucleic acids can form a variety of structural motifs which is thought to have biological significance. Stem-loop Stem-loop intramolecular base pairing is a pattern that can occur in single-stranded DNA or, more commonly, in RNA. [2] The structure is also known as a hairpin or hairpin loop.

  4. Loop-mediated isothermal amplification - Wikipedia

    en.wikipedia.org/wiki/Loop-mediated_isothermal...

    Loop-mediated isothermal amplification (LAMP) is a single-tube technique for the amplification of DNA [2] for diagnostic purposes and a low-cost alternative to detect certain diseases. [3] LAMP is an isothermal nucleic acid amplification technique.

  5. Palindromic sequence - Wikipedia

    en.wikipedia.org/wiki/Palindromic_sequence

    A: Palindrome, B: Loop, C: Stem. A palindromic sequence is a nucleic acid sequence in a double-stranded DNA or RNA molecule whereby reading in a certain direction (e.g. 5' to 3') on one strand is identical to the sequence in the same direction (e.g. 5' to 3') on the complementary strand. This definition of palindrome thus depends on ...

  6. Reverse Transcription Loop-mediated Isothermal Amplification

    en.wikipedia.org/wiki/Reverse_Transcription_Loop...

    Reverse transcription loop-mediated isothermal amplification (RT-LAMP) is a one step nucleic acid amplification method to multiply specific sequences of RNA. It is used to diagnose infectious disease caused by RNA viruses .

  7. DNA-binding domain - Wikipedia

    en.wikipedia.org/wiki/DNA-binding_domain

    The basic helix-loop-helix (bHLH) domain is found in some transcription factors and is characterized by two alpha helices (α-helixes) connected by a loop. One helix is typically smaller and due to the flexibility of the loop, allows dimerization by folding and packing against another helix. The larger helix typically contains the DNA-binding ...

  8. Loop modeling - Wikipedia

    en.wikipedia.org/wiki/Loop_modeling

    Loop modeling is a problem in protein structure prediction requiring the prediction of the conformations of loop regions in proteins with or without the use of a structural template. Computer programs that solve these problems have been used to research a broad range of scientific topics from ADP to breast cancer .

  9. Arginylglycylaspartic acid - Wikipedia

    en.wikipedia.org/wiki/Arginylglycylaspartic_acid

    Arginylglycylaspartic acid (RGD) is the most common peptide motif responsible for cell adhesion to the extracellular matrix (ECM), ...