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5: Highly suggestive of malignancy; 6: Known biopsy-proven malignancy; An incomplete (BI-RADS 0) classification warrants either an effort to ascertain prior imaging for comparison, or to call the patient back for additional views and/or higher quality films. A BI-RADS classification of 4 or 5 warrants biopsy to further evaluate the offending ...
The ability to invade surrounding tissue and metastasise is a hallmark of cancer.. The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities.
Malignancy (from Latin male 'badly' and -gnus 'born') is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer.
Advanced Placement (AP) Human Geography (also known as AP Human Geo, AP Geography, APHG, AP HuGe, APHug, AP Human, HuGS, AP HuGo, or HGAP) is an Advanced Placement social studies course in human geography for high school, usually freshmen students in the US, culminating in an exam administered by the College Board. [1]
The absence of a pathognomonic sign does not rule out the disease. Labelling a sign or symptom "pathognomonic" represents a marked intensification of a "diagnostic" sign or symptom. The word is an adjective of Greek origin derived from πάθος pathos 'disease' and γνώμων gnomon 'indicator' (from γιγνώσκω gignosko 'I know, I ...
Malignant transformation is the process by which cells acquire the properties of cancer. This may occur as a primary process in normal tissue, or secondarily as malignant degeneration of a previously existing benign tumor .
Cells in pre-malignant and malignant neoplasms evolve by natural selection. [1] [2] This accounts for how cancer develops from normal tissue and why it has been difficult to cure. There are three necessary and sufficient conditions for natural selection, all of which are met in a neoplasm: There must be variation in the population.
Pre-malignant tissue can have a distinctive appearance under the microscope. Among the distinguishing traits of a pre-malignant lesion are an increased number of dividing cells, variation in nuclear size and shape, variation in cell size and shape, loss of specialized cell features, and loss of normal tissue organization.