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A common presentation of sleep apnea in children with autism is insomnia. [67] All known genetic syndromes which are linked to autism have a high prevalence of sleep apnea. The prevalence of sleep apnea in Down's Syndrome is 50% - 100%. [68] Sleep problems and OSA in this population have been linked to language development. [69]
Mechanism of autism. The mechanisms of autism are the molecular and cellular processes believed to cause or contribute to the symptoms of autism. Multiple processes are hypothesized to explain different autism spectrum features. These hypotheses include defects in synapse structure and function, [1][2] reduced synaptic plasticity, [3] disrupted ...
[29] [30] The WHO estimates about 1 in 100 children had autism between 2012 and 2021, as that was the average estimate in studies during that period, with a trend of increasing prevalence over time. [b] [9] [10] This increasing prevalence has reinforced the myth perpetuated by anti-vaccine activists that autism is caused by vaccines. [31]
A 2003 review of epidemiological studies of children found autism rates ranging from 0.03 to 4.84 per 1,000, with the ratio of autism to Asperger syndrome ranging from 1.5:1 to 16:1; [145] combining the geometric mean ratio of 5:1 with a conservative prevalence estimate for autism of 1.3 per 1,000 suggests indirectly that the prevalence of AS ...
The Checklist for Autism in Toddlers (CHAT), a tool for diagnosing autism in children aged 18–24 months, was first published in December 1992 by Simon Baron-Cohen, Jane Allen and Christopher Gillberg. [352] Simon Baron-Cohen and others also developed another test for autism in 18-month-olds, which was published in February 1996. [353]
Epigenetics of autism. Autism spectrum disorder (ASD) refers to a variety of conditions typically identified by challenges with social skills, communication, speech, and repetitive sensory-motor behaviors. The 11th International Classification of Diseases (ICD-11), released in January 2021, characterizes ASD by the associated deficits in the ...
Classic autism. Classic autism, also known as childhood autism, autistic disorder, (early) infantile autism, infantile psychosis, Kanner's autism, Kanner's syndrome, or (formerly) just autism, is a neurodevelopmental condition first described by Leo Kanner in 1943. It is characterized by atypical and impaired development in social interaction ...
Heritability of autism. The heritability of autism is the proportion of differences in expression of autism that can be explained by genetic variation; if the heritability of a condition is high, then the condition is considered to be primarily genetic. Autism has a strong genetic basis. Although the genetics of autism are complex, autism ...