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His work focused on the role of lipid and lipoprotein metabolism in human disease, [8] and specifically the development of an RBC omega-3 index. [1] [2] [3] In 2009, he chaired an American Heart Association science advisory on Omega-6 fatty acids and cardiovascular disease. [9] He has authored >300 manuscripts in peer-reviewed literature. [10]
An omega−3 fatty acid is a fatty acid with multiple double bonds, where the first double bond is between the third and fourth carbon atoms from the end of the carbon atom chain. "Short-chain" omega−3 fatty acids have a chain of 18 carbon atoms or less, while "long-chain" omega−3 fatty acids have a chain of 20 or more.
Omega−3 fatty acids are important for normal metabolism. [ 2 ] Mammals are unable to synthesize omega−3 fatty acids, but can obtain the shorter-chain omega−3 fatty acid ALA (18 carbons and 3 double bonds) through diet and use it to form the more important long-chain omega−3 fatty acids, EPA (20 carbons and 5 double bonds) and then from ...
In physiological literature, GLA is designated as 18:3 (n−6). GLA is a carboxylic acid with an 18-carbon chain and three cis double bonds. It is a regioisomer of α-linolenic acid, which is a polyunsaturated n−3 (omega-3) fatty acid, found in rapeseed canola oil, soybeans, walnuts, flax seed (linseed oil), perilla, chia, and hemp seed.
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Vitamin D and Omega-3 Trial (VITAL) [1] was a clinical trial designed to investigate the use of daily dietary supplements of vitamin D and fish oil.. The sponsor of the study was Brigham and Women's Hospital, collaborating with The National Cancer Institute, National Heart, Lung, and Blood Institute, Office of Dietary Supplements, National Institute of Neurological Disorders and Stroke ...
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