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Anastrozole, sold under the brand name Arimidex among others, is an antiestrogenic medication used in addition to other treatments for breast cancer. [6] [7] Specifically it is used for hormone receptor-positive breast cancer. [7] It has also been used to prevent breast cancer in those at high risk. [7] It is taken by mouth. [7]
Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.Modalities include antiestrogens or estrogen blockers such as selective estrogen receptor modulators (SERMs) like tamoxifen, selective estrogen receptor degraders like fulvestrant, and aromatase inhibitors like anastrozole and ovariectomy.
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
Elle Macpherson reveals ‘shock’ breast cancer diagnosis, refused chemotherapy from 32 doctors: ‘It was unexpected’ Nika Shakhnazarova, Tracy Swartz September 3, 2024 at 6:57 AM
Observational studies of systemic HRT after breast cancer are generally reassuring. If HRT is necessary after breast cancer, estrogen-only therapy or estrogen therapy with a progestogen may be safer options than combined systemic therapy. [80] In women who are BRCA1 or BRCA2 mutation carriers, HRT does not appear to impact breast cancer risk. [81]
As of 2023, Mayo Clinic Hospital in Arizona has been ranked No.1 in Arizona and the Phoenix metro area as part of U.S. News & World Report’s “Best Hospitals” rankings. In addition, for a sixth consecutive year, Mayo Clinic in Arizona was recognized on the "Best Hospitals Honor Roll" which recognizes the top 20 hospitals in the nation. [13]
The use of high-dose estrogen therapy in breast cancer has mostly been superseded by antiestrogen therapy due to the improved safety profile of the latter. [17] High-dose estrogen therapy was the standard of care for the palliative treatment of breast cancer in women up to the late 1970s or early 1980s. [18
Proton beam therapy has been shown to be just as effective as traditional chemotherapy, with fewer side effects and less treatment time.
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