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The Journal of Extracellular Vesicles, JEV, is a peer-reviewed open-access scientific journal of the International Society for Extracellular Vesicles (ISEV). As one of two official journals of ISEV, the other being the Journal of Extracellular Biology, JEV covers research on lipid bilayer-delimited particles known as extracellular vesicles (EVs).
To disseminate research in the field, the society established the peer-reviewed open access Journal of Extracellular Vesicles in 2012. [12] The journal was initially published by Co-Action Publishing, by Taylor & Francis from 2016-2020, and by Wiley since 2020.
Extracellular vesicles (EVs) are lipid bilayer-delimited particles that are naturally released from almost all types of cells but, unlike a cell, cannot replicate. EVs range in diameter from near the size of the smallest physically possible unilamellar liposome (around 20-30 nanometers) to as large as 10 microns or more, although the vast majority of EVs are smaller than 200 nm.
Consequently, there is a growing interest in clinical applications of EVs as biomarkers and therapies alike, [15] prompting establishment of an International Society for Extracellular Vesicles (ISEV) and a scientific journal devoted to EVs, the Journal of Extracellular Vesicles.
Witwer is an associate editor of the Journal of Extracellular Vesicles and a member of the editorial boards of Clinical Chemistry and AIDS. [1] [15] He was instrumental in the founding of a second ISEV journal, the Journal of Extracellular Biology. [16]
Microvesicles (ectosomes, or microparticles) are a type of extracellular vesicle (EV) that are released from the cell membrane. [1] In multicellular organisms, microvesicles and other EVs are found both in tissues (in the interstitial space between cells) and in many types of body fluids. [ 2 ]
Clotilde Théry is a professor and INSERM director of research (DR2) at Institut Curie in Paris, France. [1] [2] She is president of the International Society for Extracellular Vesicles (ISEV), where she previously served as founding secretary general and as editor-in-chief of the Journal of Extracellular Vesicles.
The Extracellular Vesicles are small partials that are normally discharged and have boundaries that are formed by a lipid bilayer. Although cells can replicate, extracellular vesicle is not able to. In the extracellular vesical, things that consist of the stem cell secretome and are being packed are organelles, mRNA, miRNA, and proteins. [4]