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In hypokalemic periodic paralysis, arginine residues making up the voltage sensor of Na v 1.4 are mutated. The voltage sensor comprises the S4 alpha helix of each of the four transmembrane domains (I-IV) of the protein, and contains basic residues that only allow entry of the positive sodium ions at appropriate membrane voltages by blocking or opening the channel pore.
[3] [4] In 1967 they were bronze medalists. [5] However, between 1971 and 1991 , South Africa was unable to compete because of the sporting boycott during the apartheid era . [ 4 ] [ 6 ] In 1995 , South Africa returned and with an all-white team coached by Marlene Wagner, captained by Debbie Hamman and featuring Irene van Dyk and Elize Kotze ...
The professional jury of each country awards a set of 12, 10, 8–1 points to 10 songs. Viewers around the world vote for 3 songs, and their votes are distributed proportionally. The votes of the jury and the audience make up 50% of all votes. 2024 ← Junior Eurovision Song Contest
Facebook founder Mark Zuckerberg resisted buyout offers, suggesting the company was "definitely in no rush." For years, Facebook and Zuckerberg resisted both buyouts and taking the company public. The main reason that the company decided to go public is because it crossed the threshold of 500 shareholders, according to Reuters financial blogger ...
The Semantic Web, sometimes known as Web 3.0 (not to be confused with Web3), is an extension of the World Wide Web through standards [1] set by the World Wide Web Consortium (W3C). The goal of the Semantic Web is to make Internet data machine-readable .
Zeitz MOCAA opened on September 22, 2017 [1] as the largest museum of contemporary art from Africa and its diaspora. [2] The museum is located in the Silo District at the Victoria & Alfred Waterfront in Cape Town. A retail and hospitality property, the Waterfront receives around 24 million local and international visitors per year. [3]
Nexus S – 4" phone running Android 4.1 "Jelly Bean" Nest Learning Thermostat (first generation) – smart thermostat; Galaxy Nexus – 4.7" phone running Android 4.3 "Jelly Bean" Nexus Q – media streaming entertainment device in the Google Nexus product family; Nexus 7 (2012) – 7" tablet running Android 5.1 "Lollipop"
American YouTube personality MrBeast is the most-subscribed channel on YouTube, with 347 million subscribers as of January 2025.. A subscriber to a channel on the American video-sharing platform YouTube is a user who has chosen to receive the channel's content by clicking on that channel's "Subscribe" button, and each user's subscription feed consists of videos published by channels to which ...