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A Basophil granulocyte stains dark purple upon H&E staining. Basophilic is a technical term used by pathologists. It describes the appearance of cells, tissues and cellular structures as seen through the microscope after a histological section has been stained with a basic dye. The most common such dye is haematoxylin.
Basophils contain large cytoplasmic granules which obscure the cell nucleus under the microscope when stained. However, when unstained, the nucleus is visible and it usually has two lobes . [ 7 ] The mast cell , another granulocyte, is similar in appearance and function.
A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...
The cytoplasm of basophils contains a varied amount of granules; these granules are usually numerous enough to partially conceal the nucleus. Granule contents of basophils are abundant with histamine, heparin, chondroitin sulfate, peroxidase, platelet-activating factor, and other substances. [23]
An anterior pituitary basophil is a type of cell in the anterior pituitary which manufactures hormones. It is called a basophil because it is basophilic (readily takes up bases), and typically stains a relatively deep blue or purple. [1] These basophils are further classified by the hormones they produce.
The function of promyelocytes are closely linked to their differentiation into mature granulocytes, which include neutrophils, eosinophils, and basophils. [ citation needed ] These functions are essential for innate immunity and host defense mechanisms, including phagocytosis , inflammation , and immune surveillance.
Hyaline cartilage coloured with the toluidine blue, in wich you can observe a strong metachromasia of the ground substance. View through optical microscope, 40x magnification. Metachromasia (var. metachromasy ) is a characteristic change in the color of staining carried out in biological tissues , exhibited by certain dyes when they bind to ...
PRG2 is a 117-residue protein that predominates in eosinophil granules. It is a potent enzyme against helminths and is toxic towards bacteria and mammalian cells in vitro . The eosinophil major basic protein also causes the release of histamine from mast cells and basophils , and activates neutrophils and alveolar macrophages .
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