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The canonical Wnt pathway leads to regulation of gene transcription, and is thought to be negatively regulated in part by the SPATS1 gene. [4] The noncanonical planar cell polarity pathway regulates the cytoskeleton that is responsible for the shape of the cell. The noncanonical Wnt/calcium pathway regulates calcium inside the cell.
Both non-canonical E-boxes and E-box-like sequences are crucial for circadian oscillation. Recent research on this forms an hypothesis that either a canonical or non-canonical E-box followed by an E-box like sequence with 6 base pair interval in between is a necessary combination for circadian transcription. [ 21 ]
Moreover, generation of the canonical and non-canonical dimers, viz RelA:p50 and RelB:p52, within the cellular milieu are mechanistically interlinked. [47] These analyses suggest that an integrated NF-κB system network underlies activation of both RelA and RelB containing dimer and that a malfunctioning canonical pathway will lead to an ...
The non-canonical books referenced in the Bible includes non-Biblical cultures and lost works of known or unknown status. By the "Bible" is meant those books recognized by Christians and Jews as being part of Old Testament (or Tanakh) as well as those recognized by most Christians as being part of the Biblical apocrypha or of the Deuterocanon.
Developing software for pattern recognition is a major topic in genetics, molecular biology, and bioinformatics.Specific sequence motifs can function as regulatory sequences controlling biosynthesis, or as signal sequences that direct a molecule to a specific site within the cell or regulate its maturation.
While canonical Watson-Crick base pairs are most prevalent and are commonly observed in a majority of chromosomal DNA and in most functional RNAs, presence of stable non-canonical base pairs is also extremely significant in DNA biology. An example of non-Watson-Crick, or non-canonical, base pairing can be found at the ends of chromosomal DNA.
The three books of Meqabyan are often called the "Ethiopian Maccabees", but are completely different in content from the books of Maccabees that are known or have been canonized in other traditions. Finally, the Book of Joseph ben Gurion, or Pseudo-Josephus, is a history of the Jewish people thought to be based upon the writings of Josephus.
The canon of the New Testament is the set of books many modern Christians regard as divinely inspired and constituting the New Testament of the Christian Bible.For most churches, the canon is an agreed-upon list of 27 books [1] that includes the canonical Gospels, Acts, letters attributed to various apostles, and Revelation.