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  2. Heart valve - Wikipedia

    en.wikipedia.org/wiki/Heart_valve

    A heart valve is a biological one-way valve that allows blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow through the heart. Heart valves are opened or closed by a difference in blood pressure on each side. [1] [2] [3]

  3. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    The cardiomyocytes make up the bulk (99%) of cells in the atria and ventricles. These contractile cells respond to impulses of action potential from the pacemaker cells and are responsible for the contractions that pump blood through the body. The pacemaker cells make up just (1% of cells) and form the conduction system of the heart.

  4. Artificial heart valve - Wikipedia

    en.wikipedia.org/wiki/Artificial_heart_valve

    One of the major drawbacks of mechanical heart valves is that they are associated with an increased risk of blood clots. Clots formed by red blood cell and platelet damage can block blood vessels leading to stroke. People with mechanical valves need to take anticoagulants (blood thinners), such as warfarin, for the rest of their life. [16]

  5. Mitral valve - Wikipedia

    en.wikipedia.org/wiki/Mitral_valve

    A valve prolapse can result in mitral insufficiency, which is the regurgitation or backflow of blood from the left ventricle to the left atrium due to the incomplete closure of the valve causing a systolic murmur heard at the apex of the heart. This increase in pressure in the left atrium and pulmonary circuit can lead to symptoms like fatigue ...

  6. Heart - Wikipedia

    en.wikipedia.org/wiki/Heart

    Blood flow through the valves Blood flow through the heart Video explanation of blood flow through the heart. The heart functions as a pump in the circulatory system to provide a continuous flow of blood throughout the body. This circulation consists of the systemic circulation to and from the body and the pulmonary circulation to and from the ...

  7. Tissue engineering of heart valves - Wikipedia

    en.wikipedia.org/wiki/Tissue_engineering_of...

    Furthermore, cells release reactive oxygen species and cytokines, which cause secondary damage to surrounding tissue. [17] These chemical factors then proceed to promote the recruitment of other immune responsive cells such as monocytes or white blood cells, which help foster the formation of a blood clot and protein-rich matrix. [citation needed]

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  9. Circulatory system - Wikipedia

    en.wikipedia.org/wiki/Circulatory_system

    In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [1] [2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).