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Obesity hypoventilation syndrome is defined as the combination of obesity and an increased blood carbon dioxide level during the day that is not attributable to another cause of excessively slow or shallow breathing. [2] The most effective treatment is weight loss, but this may require bariatric surgery to achieve. [3]
The term "Pickwickian syndrome" that is sometimes used for the syndrome was coined by the famous early 20th-century physician William Osler, who must have been a reader of Charles Dickens. The description of Joe, "the fat boy" in Dickens's novel The Pickwick Papers , is an accurate clinical picture of an adult with obstructive sleep apnea syndrome.
Pickwickian syndrome, a medical disease named from the Dickens novel; Don Pickwick (1925–2004), Welsh footballer; Eleazer Pickwick (1748 or 1749–1837), British businessman; Pickwick Book Shop, a defunct bookshop in Hollywood, California
The prognosis of rigid spine syndrome is variable and can be influenced by several factors, including the severity of symptoms, the age of onset, and the effectiveness of treatment. In general, the condition is progressive, meaning that symptoms tend to worsen over time. However, the rate of progression can vary widely among affected individuals.
Symptomatic treatment, supportive care, supportive therapy, or palliative treatment is any medical therapy of a disease that only affects its symptoms, not the underlying cause. It is usually aimed at reducing the signs and symptoms for the comfort and well-being of the patient, but it also may be useful in reducing organic consequences and ...
Medically unexplained physical symptoms (MUPS or MUS) are symptoms for which a treating physician or other healthcare providers have found no medical cause, or whose cause remains contested. [1] In its strictest sense, the term simply means that the cause for the symptoms is unknown or disputed—there is no scientific consensus .
PI3kinase. The pathophysiology of activated PI3K delta syndrome has several aspects. [2] The normal function has P110δ (PI3K) involved in immune system regulation. [9]P110δ effect is not limited to the immune system; P110δ has a presence in transformed epithelial cells and cell adhesion molecules (airway inflammation), and research has been done on the possibility of P110δ in the nervous ...
Treatment Supportive Care Spinal and bulbar muscular atrophy ( SBMA ), popularly known as Kennedy's disease , is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.