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Three different forms of nitroglycerin: intravenous, sublingual spray, and the nitroglycerin patch. Nitroglycerin is used for the treatment of angina, acute myocardial infarction, severe hypertension, and acute coronary artery spasms. [1] [12] It may be administered intravenously, as a sublingual spray, or as a patch applied to the skin.
William Murrell (1853–1912) was an English physician, clinical pharmacologist, and toxicologist. Murrell is best known for being one of the first to recognize the clinical benefits of glyceryl trinitrate (also known as nitroglycerin) for the management of patients with angina pectoris.
The buccal mucosa, along with the gingival and sublingual mucosa, is part of the oral mucosa. [15] It is composed of non-keratinised tissue. Unlike intestinal and nasal mucosae, it lacks tight junctions and is instead equipped with loose intercellular links of desmosomes, gap junctions and hemidesmosomes. [7]
Nitroglycerin (NG) (alternative spelling of nitroglycerine), also known as trinitroglycerol (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a dense, colorless or pale yellow, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester.
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product.
Nitroglycerin patches are sometimes prescribed for the treatment of angina in lieu of sublingual pills. Transdermal scopolamine is commonly used as a treatment for motion sickness. [8] The anti-hypertensive drug clonidine is available in transdermal patch form. [9]
CHART #4: SIDE-BY-SIDE COMPARISON OF REPUBLICAN CANDIDATESÕ HEALTH PLANS By Susan J. Blumenthal, M.D., Jessica B. Rubin, Michelle E. Treseler, Jefferson Lin, and David Mattos*
The sublingual route may also be used for vaccines against various infectious diseases. Thus, preclinical studies have found that sublingual vaccines can be highly immunogenic and may protect against influenza virus [4] [5] and Helicobacter pylori, [6] but sublingual administration may also be used for vaccines against other infectious diseases.
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